Nancy Guthrie disappearance: Day 22 latest updates

Sunday marks the third week since 84-year-old Nancy Guthrie, the mother of NBC "Today" show host Savannah Guthrie, disappeared from her Tucson-area home.

Why the Nancy Guthrie investigation is facing "mixed" DNA complications

DNA samples containing multiple profiles are hindering the use of national databases in the Nancy Guthrie missing person case, according to the Pima County Sheriff’s Department.

Nancy Guthrie disappearance: Day 21 latest updates

Saturday marks Day 21 since Nancy Guthrie, the 84-year-old mother of NBC "Today" show host Savannah Guthrie, disappeared from her Tucson-area home. Investigators believe she was taken against her will.

Nancy Guthrie disappearance: Day 20 latest updates

Friday marks Day 20 since Nancy Guthrie, the 84-year-old mother of NBC "Today" show host Savannah Guthrie, disappeared from her Tucson-area home. Investigators believe she was taken against her will.

Nancy Guthrie disappearance: Day 19 latest updates

Thursday marks the 19th day since Nancy Guthrie, the 84-year-old mother of NBC "Today" show host Savannah Guthrie, disappeared from her Tucson-area home. Investigators believe she was taken against her will.

Sheriff defends Nancy Guthrie investigation amid mounting criticism

The sheriff leading a team of hundreds of investigators in the search for 84-year-old Nancy Guthrie is responding to mounting criticism over the handling of the case on Thursday.

Nancy Guthrie disappearance: Day 18 latest updates

Feb. 18 marks the 18th day since Nancy Guthrie, the 84-year-old mother of NBC "Today" show host Savannah Guthrie, disappeared from her Tucson-area home. Investigators believe she was taken against her will.

Nancy Guthrie: TMZ receives 'highly sophisticated' ransom demand

The note, according to TMZ's report, contains “a highly sophisticated demand" that involves a cryptocurrency other than Bitcoin, as well as graphic descriptions of the consequences if the ransom is not paid.

Nancy Guthrie: 'Biological evidence' found at her Catalina Foothills home

Nancy Guthrie, 84, has been missing for 18 days after she was taken from her Catalina Foothills home, and in the meantime, the sheriff's department released information Wednesday about "biological evidence" being found at the scene of the crime.

Nancy Guthrie disappearance: Day 17 latest updates

Feb. 17 marks the seventeenth day since Nancy Guthrie, the 84-year-old mother of NBC "Today" show host Savannah Guthrie, disappeared from her Tucson-area home. Investigators believe she was taken against her will.

‘Just let her go’: Sheriff issues plea to suspect in Nancy Guthrie's disappearance

DNA tests on a glove found near Nancy Guthrie’s home yielded no matches in a national database. Pima County Sheriff Chris Nanos, citing a continued rescue mission, urged suspects to release her at a hospital as the search enters week three.

Nancy Guthrie: DNA profile found on glove did not match anyone in CODIS system

DNA from a glove that was found on the side of the road two miles from Nancy Guthrie's Tucson-area home did not match anyone in the national database, the Pima County Sheriff's Department said.

Sheriff clears Nancy Guthrie’s family as suspects in her disappearance

Family members of Nancy Guthrie, including her children and their spouses, have been ruled out as suspects in her disappearance, the Pima County Sheriff's Department said Monday.

Nancy Guthrie disappearance: Day 16 latest updates

Over the weekend, authorities said they were awaiting final lab results for a glove found near the 84-year-old's residence that appears to match the masked suspect's glove in the surveillance video.

Savannah Guthrie releases new video to 'whoever has her': 'It's never too late'

Savannah Guthrie issued a new plea on Feb. 15 for the safe return of her 84-year-old mother, Nancy, as the suspected abduction enters its third week.

Nancy Guthrie: Glove found with DNA appears to match suspect's gloves in surveillance

An FBI spokesperson told Fox News on Sunday that out of several gloves recovered during the search for 84-year-old Nancy Guthrie, one glove appears to match the gloves of the suspect seen on surveillance footage, and it's testing to confirm a DNA match.

Nancy Guthrie disappearance: Day 15 latest updates

Feb. 15 marks the 15th day since Nancy Guthrie, the 84-year-old mother of NBC "Today" show host Savannah Guthrie, disappeared from her Tucson-area home.

Photos: The search for Nancy Guthrie in the Catalina Foothills

Two weeks into the search for 84-year-old Nancy Guthrie, these images document the intensifying law enforcement effort to find the kidnapped mother of "Today" host Savannah Guthrie.